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The U.S. Department of Health and Human Services has released new ICD-10-CM codes for the 2025 fiscal year, including important updates for categories F01–F99: Mental, Behavioral, and Neurodevelopmental Disorders. Behavioral health providers should be informed about these changes for reporting of billing codes from October 1, 2024 through September 30, 2025.

2025 ICD 10 CM Code Updates Announcement Update

The Centers for Medicare and Medicaid Services, a part of the U.S. Department of Health and Human Services, regularly updates guidelines for coding and reporting healthcare encounters using the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM). The latest 2025 codes lookup (overview of updates) for categories F01–F99 are on pages 41–44 of the newly released ICD-10-CM coding guidelines, which we have summarized below.

Updates Made to Mental, Behavioral and Neurodevelopmental Disorders (F01–F99)

The new guidelines clarify that pain disorders with psychological factors should be coded as F45.41 if the pain is exclusively psychological, or if the pain is partially psychological, a combination of Codes F45.42: Pain disorders with related psychological factors and G89: Pain, not elsewhere classified, can be used.

The biggest update for behavioral health is for “mental and behavioral disorders due to psychoactive substance use.” Disorders in remission (categories F10–F19) require prudent clinical judgment and documentation and should be classified as “substance abuse in remission” for milder cases, or “substance dependence in remission” for more severe cases. The guidelines go on to clarify that substance abuse and dependence should receive only the more severe code, with dependence being more severe than abuse. Also, the “unspecified” diagnosis for psychoactive substance use must have an association with a medical condition or substance-related disorder, such as mental or behavioral disorders. Furthermore, medical conditions from substances should receive dual coding—for instance, a patient with alcoholic pancreatitis could be coded under both K85.2: Alcohol induced acute pancreatitis and F10.20: Alcohol dependence, uncomplicated.

Lastly, the 2025 ICD-10-CM behavioral health guidelines include guidance on coding the perpetrator of Munchausen’s syndrome by proxy under category F68.A: Factitious disorder imposed on another, and on dementia (categories F01, F02, F03) requiring documentation to support the level of severity, or it should be coded as “unspecified severity” if sufficient documentation is unavailable.

ICD 10 Files and Resources

These are just the latest updates to the ICD-10 codes for mental, behavioral, and neurodevelopmental disorders. For many specific items of interest, we recommend these articles from our knowledgebase:

Finally, we recommend reviewing prior ICD-10 updates on the CMS website to be informed of the changes to categories F01 through F99 over the past few years.

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